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小組
長壽
長壽
發起討論
長壽
4 個討論
只看精華帖
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這算長壽嗎？
chenmx00
? 最后回復
ashref
?
2020-09-03 10:23
4023
6
? 來自相關小組
測測自己的長壽可能性
微笑的ROBO1基因
? 最后回復
zjhnyy88
?
2017-12-08 23:54
3366
5
? 來自相關小組
這個壽命結果是偏好還是偏壞呀？大家平均水平是多少？
hfm777
? 最后回復
josia851118
?
2016-12-20 17:17
4890
8
? 來自相關小組
端粒酶較短，壽命長的可能性一般。但是拇指是向上的？搞反了？
寬容的MYH7基因
? 最后回復
papayawoo
?
2016-08-04 20:24
4599
4
? 來自相關小組
發起討論
長壽
4 個討論
相關基因
MYNN
位點：RS10936599
FAM98B
位點：RS11073328
APOC3
位點：RS2542052
FOXO3
位點：RS2764264
位點：RS2802288
位點：RS2802292
CETP
位點：RS5882
KL
位點：RS9536314
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Houlston RS, et al. Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33. 2010
Jones AM, et al. TERC polymorphisms are associated both with susceptibility to colorectal cancer and with longer telomeres. 2012
International Multiple Sclerosis Genetics Consortium, et al. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. 2011
Lubbe SJ, et al. Relationship between 16 susceptibility loci and colorectal cancer phenotype in 3146 patients. 3146
Codd V, et al. Identification of seven loci affecting mean telomere length and their association with disease. 2013
Weinhold N, et al. Inherited genetic susceptibility to monoclonal gammopathy of unknown significance. 2014
Speedy HE, et al. A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia. 2014
Carvajal-Carmona LG, et al. Much of the genetic risk of colorectal cancer is likely to be mediated through susceptibility to adenomas. 2013
Figueroa JD, et al. Genome-wide association study identifies multiple loci associated with bladder cancer risk. 2014
Burnett-Hartman AN, et al. Variation in the association between colorectal cancer susceptibility loci and colorectal polyps by polyp type. 2014
Ding H, et al. Association between previously identified loci affecting telomere length and coronary heart disease (CHD) in Han Chinese population. 2014
Real LM, et al. A colorectal cancer susceptibility new variant at 4q26 in the Spanish population identified by genome-wide association analysis. 2014
Chubb D, et al. Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk. 2013
Sebastiani P, et al. Genetic signatures of exceptional longevity in humans. 2010
Armstrong DL, et al. GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region. 2014
Atzmon G, et al. Lipoprotein genotype and conserved pathway for exceptional longevity in humans. 2006
Delgado-Lista J, et al. Effects of variations in the APOA1/C3/A4/A5 gene cluster on different parameters of postprandial lipid metabolism in healthy young men. 2010
Novelli V, et al. Lack of replication of genetic associations with human longevity. 2008
Penco S, et al. New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic background. 2008
Liu Y, et al. Pharmacogenetic association of the APOA1/C3/A4/A5 gene cluster and lipid responses to fenofibrate: the genetics of lipid-lowering drugs and diet network study. 2009
Wang X, et al. A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients. 2009
Zee RY, et al. Genetic risk factors in recurrent venous thromboembolism: A multilocus, population-based, prospective approach. 2009
Wheeler HE, et al. Genetics and genomics of human ageing. 2011
Soerensen M, et al. Replication of an association of variation in the FOXO3A gene with human longevity using both case-control and longitudinal data. 2010
Anselmi CV, et al. Association of the FOXO3A locus with extreme longevity in a southern Italian centenarian study. 2009
Willcox BJ, et al. FOXO3A genotype is strongly associated with human longevity. 2008
Flachsbart F, et al. Association of FOXO3A variation with human longevity confirmed in German centenarians. 2009
Di Bona D, et al. Association between genetic variations in the insulin/insulin-like growth factor (Igf-1) signaling pathway and longevity: a systematic review and meta-analysis. 2015
Vieira AR, et al. Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts. 2008
Flachsbart F, et al. Association of FOXO3A variation with human longevity confirmed in German centenarians. 2009
Anselmi CV, et al. Association of the FOXO3A locus with extreme longevity in a southern Italian centenarian study. 2009
Willcox BJ, et al. FOXO3A genotype is strongly associated with human longevity. 2008
Anselmi CV, et al. Association of the FOXO3A locus with extreme longevity in a southern Italian centenarian study. 2009
Magno LA, et al. Genetic variations in FOXO3A are associated with Bipolar Disorder without confering vulnerability for suicidal behavior. 2011
Flachsbart F, et al. Association of FOXO3A variation with human longevity confirmed in German centenarians. 2009
Banasik K, et al. The FOXO3A rs2802292 G-allele associates with improved peripheral and hepatic insulin sensitivity and increased skeletal muscle-FOXO3A mRNA expression in twins. 2011
Wheeler HE, et al. Genetics and genomics of human ageing. 2011
Di Bona D, et al. Association between genetic variations in the insulin/insulin-like growth factor (Igf-1) signaling pathway and longevity: a systematic review and meta-analysis. 2015
Forte G, et al. Characterization of the rs2802292 SNP identifies FOXO3A as a modifier locus predicting cancer risk in patients with PJS and PHTS hamartomatous polyposis syndromes. 2014
Sanders AE, et al. Association of a functional polymorphism in the cholesteryl ester transfer protein (CETP) gene with memory decline and incidence of dementia. 2010
Peloso GM, et al. Common genetic variation in multiple metabolic pathways influences susceptibility to low HDL-cholesterol and coronary heart disease. 2010
Yu L, et al. The CETP I405V polymorphism is associated with an increased risk of Alzheimer's disease. 2012
Papp AC, et al. Cholesteryl Ester Transfer Protein (CETP) polymorphisms affect mRNA splicing, HDL levels, and sex-dependent cardiovascular risk. 2012
Bansal A, et al. Association testing by DNA pooling: an effective initial screen. 2002
Ding C, et al. Direct molecular haplotyping of long-range genomic DNA with M1-PCR. 2003
Terán-García M, et al. Effects of cholesterol ester transfer protein (CETP) gene on adiposity in response to long-term overfeeding. 2008
Johnson W, et al. No association of CETP genotype with cognitive function or age-related cognitive change. 2007
Novelli V, et al. Lack of replication of genetic associations with human longevity. 2008
Sebastiani P, et al. A hierarchical and modular approach to the discovery of robust associations in genome-wide association studies from pooled DNA samples. 2008
Penco S, et al. New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic background. 2008
Enquobahrie DA, et al. Cholesterol ester transfer protein, interleukin-8, peroxisome proliferator activator receptor alpha, and Toll-like receptor 4 genetic variations and risk of incident nonfatal myocardial infarction and ischemic stroke. 2008
Meiner V, et al. Cholesteryl ester transfer protein (CETP) genetic variation and early onset of non-fatal myocardial infarction. 2008
Lu Y, et al. Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations. 2008
Boes E, et al. Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review. 2009
Wang X, et al. A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients. 2009
Zee RY, et al. Genetic risk factors in recurrent venous thromboembolism: A multilocus, population-based, prospective approach. 2009
Lins TC, et al. TagSNP transferability and relative loss of variability prediction from HapMap to an admixed population. 2009
Chasman DI, et al. Genetic loci associated with plasma concentration of low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, apolipoprotein A1, and Apolipoprotein B among 6382 white women in genome-wide analysis with replication. 2008
Ridker PM, et al. Polymorphism in the CETP gene region, HDL cholesterol, and risk of future myocardial infarction: Genomewide analysis among 18 245 initially healthy women from the Women's Genome Health Study. 2009
Legry V, et al. Associations between common genetic polymorphisms in the liver X receptor alpha and its target genes with the serum HDL-cholesterol concentration in adolescents of the HELENA Study. 2011
Clifford AJ, et al. Gender and single nucleotide polymorphisms in MTHFR, BHMT, SPTLC1, CRBP2, CETP, and SCARB1 are significant predictors of plasma homocysteine normalized by RBC folate in healthy adults. 2012
Wang J, et al. CETP gene polymorphisms and risk of coronary atherosclerosis in a Chinese population. 2013
Todur SP, et al. Association of CETP and LIPC Gene Polymorphisms with HDL and LDL Sub-fraction Levels in a Group of Indian Subjects: A Cross-Sectional Study. 2013
Rudkowska I, et al. Gene-diet interactions on plasma lipid levels in the Inuit population. 2013
Zhang X, et al. Different impact of high-density lipoprotein-related genetic variants on polypoidal choroidal vasculopathy and neovascular age-related macular degeneration in a Chinese Han population. 2013
Warstadt NM, et al. Serum cholesterol and variant in cholesterol-related gene CETP predict white matter microstructure. 2014
Nguyen M, et al. Infantile hypercalcemia and hypercalciuria: new insights into a vitamin D-dependent mechanism and response to ketoconazole treatment. 2010
Tangri N, et al. Lack of association of Klotho gene variants with valvular and vascular calcification in Caucasians: a candidate gene study of the Framingham Offspring Cohort. 2011
Freathy RM, et al. The functional "KL-VS" variant of KLOTHO is not associated with type 2 diabetes in 5028 UK Caucasians. 5028
Sebastiani P, et al. A hierarchical and modular approach to the discovery of robust associations in genome-wide association studies from pooled DNA samples. 2008
Paroni G, et al. Klotho locus, metabolic traits, and serum hemoglobin in hospitalized older patients: a genetic association analysis. 2012
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