More interestingly, our results showed that the risk genotypes for IMN development (A/A or A/G for HLA-DQA1 and A/A for PLA2R1) also predict response to immunosuppressive therapy and protection to renal function decline. We speculate that other genetic and environmental factors could contribute to the development of IMN in patients carrying the protective genotypes (G/G for HLA-DQA1 and A/G or G/G for PLA2R1), explaining their low likelihood of response to immunosuppressive treatment
正常的基因型應該是GG 研究中有顯著風險的是AA AG 那我這種CT的豈不是和中獎一樣??近6倍的風險 正常人的患病率是百分之10 那我不就是百分之60了……這也太真實了吧??