
健康風(fēng)險(xiǎn)能否增加酒渣鼻?RSID:rs1800629 附文獻(xiàn)
該文獻(xiàn)指出:
Rs1800629 polymorphism of of TNF-α gene in
patients with rosacea and conditionally healthy donors Uzbeks,
characterized by wide allelic diversity. Functionally unfavorable
genotype rs1800629*G/A of TNF-α gene significantly contributes
to the formation of rosacea and more associated with erythematous
stage of rosacea. The risk of development of pathology in the presence
of this genotype may be increased more than 3 times, and the
chances of forming erythematous stage of disease when it present
are increased by more than 4.5 times (χ 2=29.7; Р<0.05; OR=4.9;
95%CI 2.704–8.865). At that, wild genotype rs1800629*G/G of
TNF-α gene may be associated with a decreased risk of developing
the disease in carriers of this genotype.
?
不過我查了下我自己的,應(yīng)該屬于低風(fēng)險(xiǎn)型。
然而事實(shí)是我和我爸爸,我爺爺都有酒渣鼻,我還是個(gè)女的。
?
更多的文獻(xiàn)我沒有再仔細(xì)查,應(yīng)該還有更多的基因位點(diǎn)數(shù)據(jù)支持,原文見附件。
?
Rs1800629 polymorphism of of TNF-α gene in
patients with rosacea and conditionally healthy donors Uzbeks,
characterized by wide allelic diversity. Functionally unfavorable
genotype rs1800629*G/A of TNF-α gene significantly contributes
to the formation of rosacea and more associated with erythematous
stage of rosacea. The risk of development of pathology in the presence
of this genotype may be increased more than 3 times, and the
chances of forming erythematous stage of disease when it present
are increased by more than 4.5 times (χ 2=29.7; Р<0.05; OR=4.9;
95%CI 2.704–8.865). At that, wild genotype rs1800629*G/G of
TNF-α gene may be associated with a decreased risk of developing
the disease in carriers of this genotype.
?
不過我查了下我自己的,應(yīng)該屬于低風(fēng)險(xiǎn)型。
然而事實(shí)是我和我爸爸,我爺爺都有酒渣鼻,我還是個(gè)女的。
?
更多的文獻(xiàn)我沒有再仔細(xì)查,應(yīng)該還有更多的基因位點(diǎn)數(shù)據(jù)支持,原文見附件。
?
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