
JAMA子刊新報道:線粒體單倍群 I, J, K, O-X, T, U , A和M的自閉癥風險較高
JAMA Psychiatry的8月23日發表的研究成果:Of 1624 patients with autism included in this study, 1299 were boys (80%) and 325 were girls (20%). Families in the Autism Genetic Resource Exchange collection (933 families, encompassing 4041 individuals: 1624 patients with ASD and 2417 healthy parents and siblings) had been previously recruited in the United States with no restrictions on age, sex, race/ethnicity, or socioeconomic status. Relative to the most common European haplogroup HHV, European haplogroups I, J, K, O-X, T, and U were associated with increased risk of ASD, as were Asian and Native American haplogroups A and M, with odds ratios ranging from 1.55 (95% CI, 1.16-2.06) to 2.18 (95% CI, 1.59-3) (adjusted?P?< .04). Hence, mtDNA haplogroup variation is an important risk factor for ASD.
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參考文獻:http://jamanetwork.com/journals/jamapsychiatry/article-abstract/2649278
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母系是B的表示沒有壓力啊
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參考文獻:http://jamanetwork.com/journals/jamapsychiatry/article-abstract/2649278
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母系是B的表示沒有壓力啊
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這個N9a的糖尿病在case組和control組的區別只是3%和5%的區別啊
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按發病率算,確實快翻倍了
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