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小組
飽和脂肪敏感性
飽和脂肪敏感性
發起討論
飽和脂肪敏感性
10 個討論
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為什么我現在胖了啊
九歌96
? 最后回復
WeGene_750F6529
?
2023-06-25 16:33
1459
3
? 來自相關小組
各色DNA都有瘦素項（基因位點rs10487505為G？咋的？？
沉著的CDH2基因
? 最后回復
Creator0
?
2023-01-25 11:30
1698
4
? 來自相關小組
子女推算結果
karenng
? 最后回復
west
?
2019-08-01 10:30
2979
4
? 來自相關小組
飽和脂肪敏感性78，是什么意思？
grmagic
? 最后回復
luohda
?
2019-01-21 21:32
8580
11
? 來自相關小組
飽和脂肪敏感度78，但是卻是瘦子。。。
dreamery
? 最后回復
彼岸狂花
?
2018-10-17 19:32
6119
12
? 來自相關小組
飽和脂肪敏感性 高和低分別說明什麼問題
中國的SCN1A基因
? 最后回復
夜歸人
?
2018-08-07 20:38
5420
3
? 來自相關小組
請問飽和脂肪敏感度較低如何解讀
petersline
? 最后回復
sslove1988
?
2018-05-14 12:29
4841
1
? 來自相關小組
飽和脂肪敏感性顯示rs328基因為cc表示敏感性高但文獻上表示為良性
四瞬微光
? 最后回復
四瞬微光
?
2017-06-15 11:25
3967
2
? 來自相關小組
飽和脂肪酸不是好的嗎
makeachange
? 最后回復
Chipmunk
?
2017-06-13 13:12
3883
1
? 來自相關小組
什么叫飽和脂肪敏感性？
xiaoyuvax
? 最后回復
強健的PKHD1基因
?
2017-03-31 14:14
5576
3
? 來自相關小組
發起討論
飽和脂肪敏感性
10 個討論
相關基因
LRP1
位點：RS1799986
TNF, LTA
位點：RS1800629
LPL
位點：RS328
APOC1
位點：RS4420638
APOA2
位點：RS5082
CETP
位點：RS5882
位點：RS708272
LDLR
位點：RS6511720
APOA5
位點：RS662799
APOB
位點：RS693
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High fat diet modifies the association of lipoprotein lipase gene polymorphism with high density lipoprotein cholesterol in an Asian Indian population
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Willer CJ, et al. Newly identified loci that influence lipid concentrations and risk of coronary artery disease. 2008
Kathiresan S, et al. Common variants at 30 loci contribute to polygenic dyslipidemia. 2009
Burkhardt R, et al. Common SNPs in HMGCR in micronesians and whites associated with LDL-cholesterol levels affect alternative splicing of exon13. 2008
Sandhu MS, et al. LDL-cholesterol concentrations: a genome-wide association study. 2008
Kathiresan S, et al. Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. 2008
Willer CJ, et al. Newly identified loci that influence lipid concentrations and risk of coronary artery disease. 2008
Li H, et al. Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease. 2008
Webster JA, et al. Sorl1 as an Alzheimer's disease predisposition gene? 2007
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Coon KD, et al. A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease. 2007
Elliott P, et al. Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease. 2009
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Lowe JK, et al. Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae. 2009
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Waterworth DM, et al. Genetic variants influencing circulating lipid levels and risk of coronary artery disease. 2010
Okada Y, et al. Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus. 2011
Dehghan A, et al. Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. 2011
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Teslovich TM, et al. Biological, clinical and population relevance of 95 loci for blood lipids. 2010
Blom ES, et al. Does APOE explain the linkage of Alzheimer's disease to chromosome 19q13? 2008
Wallace C, et al. Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia. 2008
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Johnson AD, et al. An open access database of genome-wide association results. 2009
Schjeide BM, et al. GAB2 as an Alzheimer disease susceptibility gene: follow-up of genomewide association results. 2009
Meng YA, et al. Performance of random forest when SNPs are in linkage disequilibrium. 2009
Drenos F, et al. Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk. 2009
McKnight AJ, et al. Genetic analysis of coronary artery disease single-nucleotide polymorphisms in diabetic nephropathy. 2009
Buckham T, et al. The coronary artery disease SNP, rs4420638, is associated with diabetic nephropathy rather than end-stage renal disease. 2009
Hindorff LA, et al. Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. 2009
Heard-Costa NL, et al. NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium. 2009
Sebastiani P, et al. Genome-wide association studies and the genetic dissection of complex traits. 2009
Ding K, et al. Genome-wide association studies for atherosclerotic vascular disease and its risk factors. 2009
Liu W, et al. A simple and efficient algorithm for genome-wide homozygosity analysis in disease. 2009
Ronald J, et al. Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease. 2009
Hamid JS, et al. Using a latent growth curve model for an integrative assessment of the effects of genetic and environmental factors on multiple phenotypes. 2009
Barber MJ, et al. Genome-wide association of lipid-lowering response to statins in combined study populations. 2010
Hu M, et al. Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients. 2010
Park MH, et al. Genetic loci associated with lipid concentrations and cardiovascular risk factors in the Korean population. 2011
Deshmukh HA, et al. Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importance of Lp(a). 2012
Kamboh MI, et al. Genome-wide association study of Alzheimer's disease. 2012
Vrablík M, et al. Impact of variants within seven candidate genes on statin treatment efficacy. 2012
Aslibekyan S, et al. Variants identified in a GWAS meta-analysis for blood lipids are associated with the lipid response to fenofibrate. 2012
Park YJ, et al. Association of polymorphisms modulating low-density lipoprotein cholesterol with susceptibility, severity, and progression of rheumatoid arthritis. 2013
Fritsche LG, et al. Seven new loci associated with age-related macular degeneration. 2013
Boulenouar H, et al. Impact of APOE gene polymorphisms on the lipid profile in an Algerian population. 2013
Hopewell JC, et al. Impact of common genetic variation on response to simvastatin therapy among 18 705 participants in the Heart Protection Study. 2013
Beekman M, et al. Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study. 2013
Varga TV, et al. Genetic determinants of long-term changes in blood lipid concentrations: 10-year follow-up of the GLACIER study. 2014
Deelen J, et al. Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age. 2014
Global Lipids Genetics Consortium, et al. Discovery and refinement of loci associated with lipid levels. 2013
Keller M, et al. THOC5: a novel gene involved in HDL-cholesterol metabolism. 2013
Corella D, Peloso G, Arnett D K, et al. APOA2, dietary fat, and body mass index: replication of a gene-diet interaction in 3 independent populations[J]. Archives of internal medicine, 2009, 169(20): 1897-1906.
Sanders AE, et al. Association of a functional polymorphism in the cholesteryl ester transfer protein (CETP) gene with memory decline and incidence of dementia. 2010
Peloso GM, et al. Common genetic variation in multiple metabolic pathways influences susceptibility to low HDL-cholesterol and coronary heart disease. 2010
Yu L, et al. The CETP I405V polymorphism is associated with an increased risk of Alzheimer's disease. 2012
Papp AC, et al. Cholesteryl Ester Transfer Protein (CETP) polymorphisms affect mRNA splicing, HDL levels, and sex-dependent cardiovascular risk. 2012
Bansal A, et al. Association testing by DNA pooling: an effective initial screen. 2002
Ding C, et al. Direct molecular haplotyping of long-range genomic DNA with M1-PCR. 2003
Terán-García M, et al. Effects of cholesterol ester transfer protein (CETP) gene on adiposity in response to long-term overfeeding. 2008
Johnson W, et al. No association of CETP genotype with cognitive function or age-related cognitive change. 2007
Novelli V, et al. Lack of replication of genetic associations with human longevity. 2008
Sebastiani P, et al. A hierarchical and modular approach to the discovery of robust associations in genome-wide association studies from pooled DNA samples. 2008
Penco S, et al. New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic background. 2008
Enquobahrie DA, et al. Cholesterol ester transfer protein, interleukin-8, peroxisome proliferator activator receptor alpha, and Toll-like receptor 4 genetic variations and risk of incident nonfatal myocardial infarction and ischemic stroke. 2008
Meiner V, et al. Cholesteryl ester transfer protein (CETP) genetic variation and early onset of non-fatal myocardial infarction. 2008
Lu Y, et al. Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations. 2008
Boes E, et al. Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review. 2009
Wang X, et al. A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients. 2009
Zee RY, et al. Genetic risk factors in recurrent venous thromboembolism: A multilocus, population-based, prospective approach. 2009
Lins TC, et al. TagSNP transferability and relative loss of variability prediction from HapMap to an admixed population. 2009
Chasman DI, et al. Genetic loci associated with plasma concentration of low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, apolipoprotein A1, and Apolipoprotein B among 6382 white women in genome-wide analysis with replication. 2008
Ridker PM, et al. Polymorphism in the CETP gene region, HDL cholesterol, and risk of future myocardial infarction: Genomewide analysis among 18 245 initially healthy women from the Women's Genome Health Study. 2009
Legry V, et al. Associations between common genetic polymorphisms in the liver X receptor alpha and its target genes with the serum HDL-cholesterol concentration in adolescents of the HELENA Study. 2011
Clifford AJ, et al. Gender and single nucleotide polymorphisms in MTHFR, BHMT, SPTLC1, CRBP2, CETP, and SCARB1 are significant predictors of plasma homocysteine normalized by RBC folate in healthy adults. 2012
Wang J, et al. CETP gene polymorphisms and risk of coronary atherosclerosis in a Chinese population. 2013
Todur SP, et al. Association of CETP and LIPC Gene Polymorphisms with HDL and LDL Sub-fraction Levels in a Group of Indian Subjects: A Cross-Sectional Study. 2013
Rudkowska I, et al. Gene-diet interactions on plasma lipid levels in the Inuit population. 2013
Zhang X, et al. Different impact of high-density lipoprotein-related genetic variants on polypoidal choroidal vasculopathy and neovascular age-related macular degeneration in a Chinese Han population. 2013
Warstadt NM, et al. Serum cholesterol and variant in cholesterol-related gene CETP predict white matter microstructure. 2014
Kathiresan S, et al. Common variants at 30 loci contribute to polygenic dyslipidemia. 2009
Kathiresan S, et al. Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. 2008
Willer CJ, et al. Newly identified loci that influence lipid concentrations and risk of coronary artery disease. 2008
Miljkovic I, et al. Association analysis of 33 lipoprotein candidate genes in multi-generational families of African ancestry. 2010
Trompet S, et al. Replication of LDL GWAs hits in PROSPER/PHASE as validation for future (pharmaco)genetic analyses. 2011
Grallert H, et al. Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies. 2012
Middelberg RP, et al. Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits. 2011
Bis JC, et al. Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque. 2011
Teslovich TM, et al. Biological, clinical and population relevance of 95 loci for blood lipids. 2010
Middelberg RP, et al. Evidence of differential allelic effects between adolescents and adults for plasma high-density lipoprotein. 2012
Serre D, et al. Correction of population stratification in large multi-ethnic association studies. 2008
Linsel-Nitschke P, et al. Lifelong reduction of LDL-cholesterol related to a common variant in the LDL-receptor gene decreases the risk of coronary artery disease--a Mendelian Randomisation study. 2008
Mohlke KL, et al. Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants. 2008
Sabatti C, et al. Genome-wide association analysis of metabolic traits in a birth cohort from a founder population. 2009
Aulchenko YS, et al. Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. 2009
Franceschini N, et al. Low density lipoprotein receptor polymorphisms and the risk of coronary heart disease: the Atherosclerosis Risk in Communities Study. 2009
Deo RC, et al. Genetic differences between the determinants of lipid profile phenotypes in African and European Americans: the Jackson Heart Study. 2009
Ferrucci L, et al. Common variation in the beta-carotene 15,15'-monooxygenase 1 gene affects circulating levels of carotenoids: a genome-wide association study. 2009
Drenos F, et al. Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk. 2009
Hong MG, et al. Strategies and issues in the detection of pathway enrichment in genome-wide association studies. 2009
Murray A, et al. Common lipid-altering gene variants are associated with therapeutic intervention thresholds of lipid levels in older people. 2009
Hegele RA, et al. A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia. 2009
Ding K, et al. Genome-wide association studies for atherosclerotic vascular disease and its risk factors. 2009
Andreotti G, et al. Genetic determinants of serum lipid levels in Chinese subjects: a population-based study in Shanghai, China. 2009
Ronald J, et al. Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease. 2009
Anand SS, et al. Genetic variants associated with myocardial infarction risk factors in over 8000 individuals from five ethnic groups: The INTERHEART Genetics Study. 8000
Lettre G, et al. Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. 2011
Vrablík M, et al. Impact of variants within seven candidate genes on statin treatment efficacy. 2012
Inouye M, et al. Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis. 2012
Meirelles OD, et al. SHAVE: shrinkage estimator measured for multiple visits increases power in GWAS of quantitative traits. 2013
Xu L, et al. An association study between genetic polymorphisms related to lipoprotein-associated phospholipase A(2) and coronary heart disease. 2013
Global Lipids Genetics Consortium, et al. Discovery and refinement of loci associated with lipid levels. 2013
Bradley DT, et al. A variant in LDLR is associated with abdominal aortic aneurysm. 2013
De Caterina R, et al. Strong association of the APOA5-1131T>C gene variant and early-onset acute myocardial infarction. 2011
Corella D, et al. APOA5 gene variation modulates the effects of dietary fat intake on body mass index and obesity risk in the Framingham Heart Study. 2007
Wang J, et al. Polygenic determinants of severe hypertriglyceridemia. 2008
Liu ZK, et al. Associations of polymorphisms in the apolipoprotein A1/C3/A4/A5 gene cluster with familial combined hyperlipidaemia in Hong Kong Chinese. 2010
Ken-Dror G, et al. Different effects of apolipoprotein A5 SNPs and haplotypes on triglyceride concentration in three ethnic origins. 2010
Ariza MJ, et al. Additive effects of LPL, APOA5 and APOE variant combinations on triglyceride levels and hypertriglyceridemia: results of the ICARIA genetic sub-study. 2010
Jiang CQ, et al. A single nucleotide polymorphism in APOA5 determines triglyceride levels in Hong Kong and Guangzhou Chinese. 2010
Horvatovich K, et al. Haplotype analysis of the apolipoprotein A5 gene in obese pediatric patients. 2011
De Caterina R, et al. Strong association of the APOA5-1131T>C gene variant and early-onset acute myocardial infarction. 2011
Hong CJ, et al. Impact of apolipoprotein A5 (APOA5) polymorphisms on serum triglyceride levels in schizophrenic patients under long-term atypical antipsychotic treatment. 2012
Ward KJ, et al. Allelic drop-out may occur with a primer binding site polymorphism for the commonly used RFLP assay for the -1131T>C polymorphism of the Apolipoprotein AV gene. 2006
Pare G, et al. Genetic analysis of 103 candidate genes for coronary artery disease and associated phenotypes in a founder population reveals a new association between endothelin-1 and high-density lipoprotein cholesterol. 2007
Kathiresan S, et al. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. 2007
Liao YC, et al. Multiple genetic determinants of plasma lipid levels in Caribbean Hispanics. 2008
Serre D, et al. Correction of population stratification in large multi-ethnic association studies. 2008
Pullinger CR, et al. An apolipoprotein A-V gene SNP is associated with marked hypertriglyceridemia among Asian-American patients. 2008
Dallongeville J, et al. The APOA5 Trp19 allele is associated with metabolic syndrome via its association with plasma triglycerides. 2008
Webster RJ, et al. The association of common genetic variants in the APOA5, LPL and GCK genes with longitudinal changes in metabolic and cardiovascular traits. 2009
Boes E, et al. Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review. 2009
Perez-Martinez P, et al. Association between glucokinase regulatory protein (GCKR) and apolipoprotein A5 (APOA5) gene polymorphisms and triacylglycerol concentrations in fasting, postprandial, and fenofibrate-treated states. 2009
Liu Y, et al. Pharmacogenetic association of the APOA1/C3/A4/A5 gene cluster and lipid responses to fenofibrate: the genetics of lipid-lowering drugs and diet network study. 2009
Deo RC, et al. Genetic differences between the determinants of lipid profile phenotypes in African and European Americans: the Jackson Heart Study. 2009
Ferrucci L, et al. Common variation in the beta-carotene 15,15'-monooxygenase 1 gene affects circulating levels of carotenoids: a genome-wide association study. 2009
Lanktree MB, et al. Replication of genetic associations with plasma lipoprotein traits in a multiethnic sample. 2009
Murray A, et al. Common lipid-altering gene variants are associated with therapeutic intervention thresholds of lipid levels in older people. 2009
Hegele RA, et al. A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia. 2009
Jackson KG, et al. Introduction to the DISRUPT postprandial database: subjects, studies and methodologies. 2010
Kraja AT, et al. Fenofibrate and metabolic syndrome. 2010
Triglyceride Coronary Disease Genetics Consortium and Emerging Risk Factors Collaboration, et al. Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies. 2010
Saleheen D, et al. Genetic determinants of major blood lipids in Pakistanis compared with Europeans. 2010
Lu Y, et al. Exploring genetic determinants of plasma total cholesterol levels and their predictive value in a longitudinal study. 2010
Ong KL, et al. Association of a genetic variant in the apolipoprotein A5 gene with the metabolic syndrome in Chinese. 2011
Feitosa MF, et al. Association of gene variants with lipid levels in response to fenofibrate is influenced by metabolic syndrome status. 2011
Yin RX, et al. Interactions of the apolipoprotein A5 gene polymorphisms and alcohol consumption on serum lipid levels. 2011
Bhaskar S, et al. Association of PON1 and APOA5 gene polymorphisms in a cohort of Indian patients having coronary artery disease with and without type 2 diabetes. 2011
Liu SM, et al. Rapid genotyping of APOA5 -1131T>C polymorphism using high resolution melting analysis with unlabeled probes. 2012
Rafiq S, et al. Evaluation of seven common lipid associated loci in a large Indian sib pair study. 2012
Takeuchi F, et al. Association of genetic variants influencing lipid levels with coronary artery disease in Japanese individuals. 2012
Hishida A, et al. Associations of apolipoprotein A5 (APOA5), glucokinase (GCK) and glucokinase regulatory protein (GCKR) polymorphisms and lifestyle factors with the risk of dyslipidemia and dysglycemia in Japanese - a cross-sectional data from the J-MICC Study. 2012
Hiramatsu M, et al. Synergistic effects of genetic variants of APOA5 and BTN2A1 on dyslipidemia or metabolic syndrome. 2012
Yin RX, et al. Interactions between the apolipoprotein a1/c3/a5 haplotypes and alcohol consumption on serum lipid levels. 2013
Can Demird??en B, et al. Apolipoprotein A5 polymorphisms in Turkish population: association with serum lipid profile and risk of ischemic stroke. 2012
Hsu MC, et al. Central obesity in males affected by a dyslipidemia-associated genetic polymorphism on APOA1/C3/A4/A5 gene cluster. 2013
Iqbal R, et al. Genetic association of lipid metabolism related SNPs with myocardial infarction in the Pakistani population. 2014
Wu Y, et al. Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels. 2013
Hubacek JA, et al. The association between APOA5 haplotypes and plasma lipids is not modified by energy or fat intake: the Czech HAPIEE study. 2014
Nakatochi M, et al. Identification of an interaction between VWF rs7965413 and platelet count as a novel risk marker for metabolic syndrome: an extensive search of candidate polymorphisms in a case-control study. 2015
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